Chapter 14: Genome Assembly and Annotation Process
نویسنده
چکیده
The basic procedures used to annotate other eukaryotic genomes are essentially the same as those used to annotate the human genome. However, the overall process is adjusted to accommodate the different types of input data that are available for each organism. Genes can be annotated on any genome for which a significant number of mRNA, EST, or protein sequences are available. Other features, such as clones, STS markers, and SNPs, can also be annotated whenever the relevant data are available for an organism.
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14 . Genome Assembly and Annotation Process
The primary data produced by genome sequencing projects are often highly fragmented and sparsely annotated. This is especially true for the Human Genome Project [http://www.genome.gov/ page.cfm?pageID=10001772] as a result of its policy of releasing sequence data to the public sequence databases every day (1, 2). So that individual researchers do not have to piece together extended segments of ...
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